Anchored HTML File of EIDs

	WEB-based GEne SeT AnaLysis Toolkit

	*Translating gene lists into biological insights...*

User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:

C: the number of reference genes in the category
O: the number of genes in the gene set and also in the category
E: the expected number in the category
R: ratio of enrichment
rawP: p value from hypergeometric test
adjP: p value adjusted by the multiple test adjustment

Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway Name:Ribosome biogenesis in eukaryotes ID:03008
C=80; O=3; E=0.12; R=25.67; rawP=0.0002; adjP=0.0004
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000104356	NA	POP1	processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)	10940	ENSG00000104356
2	ENSG00000041802	NA	LSG1	large subunit GTPase 1 homolog (S. cerevisiae)	55341	ENSG00000041802
3	ENSG00000164338	NA	UTP15	UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)	84135	ENSG00000164338

Database:KEGG pathway Name:Terpenoid backbone biosynthesis ID:00900
C=15; O=2; E=0.02; R=91.27; rawP=0.0002; adjP=0.0004
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000112972	NA	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	3157	ENSG00000112972
2	ENSG00000113161	NA	HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	3156	ENSG00000113161

Database:KEGG pathway Name:Spliceosome ID:03040
C=127; O=3; E=0.19; R=16.17; rawP=0.0009; adjP=0.0012
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000136875	NA	PRPF4	PRP4 pre-mRNA processing factor 4 homolog (yeast)	9128	ENSG00000136875
2	ENSG00000167088	NA	SNRPD1	small nuclear ribonucleoprotein D1 polypeptide 16kDa	6632	ENSG00000167088
3	ENSG00000109606	NA	DHX15	DEAH (Asp-Glu-Ala-His) box polypeptide 15	1665	ENSG00000109606

Database:KEGG pathway Name:Metabolic pathways ID:01100
C=1130; O=4; E=1.65; R=2.42; rawP=0.0832; adjP=0.0832
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000112972	NA	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	3157	ENSG00000112972
2	ENSG00000170271	NA	C5orf4	chromosome 5 open reading frame 4	10826	ENSG00000170271
3	ENSG00000139547	NA	RDH16	retinol dehydrogenase 16 (all-trans)	8608	ENSG00000139547
4	ENSG00000113161	NA	HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	3156	ENSG00000113161

WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).